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Research Article

Clinical, Epidemiologic, Histopathologic and Molecular Features of an Unexplained Dermopathy

  • Michele L. Pearson,

    Affiliation: Division of TB Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • Joseph V. Selby,

    Affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America

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  • Kenneth A. Katz,

    Affiliation: HIV, STD, and Hepatitis Branch, Health and Human Services Agency, County of San Diego, San Diego, California, United States of America

    X
  • Virginia Cantrell,

    Affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America

    X
  • Christopher R. Braden,

    Affiliation: Division of Food, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • Monica E. Parise,

    Affiliation: Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Christopher D. Paddock,

    Affiliation: Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • Michael R. Lewin-Smith,

    Affiliation: Environmental Pathology, Joint Pathology Center, Silver Spring, Maryland, United States of America

    X
  • Victor F. Kalasinsky,

    Affiliation: Office of Research & Development, United States Department of Veterans Affairs, Washington, District of Columbia, United States of America

    X
  • Felicia C. Goldstein,

    Affiliation: Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, United States of America

    X
  • Allen W. Hightower,

    Affiliation: Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Arthur Papier,

    Affiliation: Department of Dermatology, University of Rochester School of Medicine, Rochester, New York, United States of America

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  • Brian Lewis,

    Affiliation: Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia, United States of America

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  • Sarita Motipara,

    Affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America

    X
  • Mark L. Eberhard mail,

    mle1@cdc.gov

    Affiliation: Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • for the Unexplained Dermopathy Study Team

    Additional membership of the Unexplained Dermopathy Study Team is provided in the Acknowledgments.

    X
  • Published: January 25, 2012
  • DOI: 10.1371/journal.pone.0029908

Reader Comments (24)

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Possible Diagnostic Test

Posted by cynt on 19 Oct 2013 at 23:53 GMT

Diagnosis:
Many infectious diseases have an abnormal odor: examples include BV and vaginal Trichomonas. Numerous patient’s with Morgellons Disease report an abnormal odor from lesions or from clothing that has been in contact with affected areas.

From my experience, this unique odor is detected by the following procedure: Soak a 100% cotton pad in acetone and swab pad over closed lesions. This liberates a pungent, unpleasant and unique odor and a faint yellow color is visible on the cotton pad. The odor and yellow tint is absent when the (acetone-saturated) pad is swabbed over unaffected areas. Additionally, this tint and odor can be transferred to towels, nylons or clothing directly or indirectly from hands or lesions.
Candidates for testing should NOT have a recent history of antibiotic use or the use of effective solvents that remove scales.

Treatment:
Clinique 2® clarifying lotion for dry combination skin used to be excellent for removing scales and reducing pruritus (itching) from Morgellons’ lesions. Now that disodium EDTA and other ingredients have been removed, this product is no longer effective.

No competing interests declared.