Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Jeffrey W. Streb; Xiaochun Long; Ting-Hein Lee; Qiang Sun; Chad M. Kitchen; Mary A. Georger; Orazio J. Slivano; William S. Blaner; Daniel W. Carr; Irwin H. Gelman; Joseph M. Miano

doi:10.1371/journal.pone.0018538

Loading metrics

Open Access

Peer-reviewed

Research Article

Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Jeffrey W. Streb,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Xiaochun Long,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Ting-Hein Lee,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Qiang Sun,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Chad M. Kitchen,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Mary A. Georger,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
Orazio J. Slivano,

Affiliation Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯
William S. Blaner,

Affiliation Department of Medicine, Columbia University, New York, New York, United States of America
⨯
Daniel W. Carr,

Affiliation Portland Veterans Affairs Medical Center, Portland, Oregon, United States of America
⨯
Irwin H. Gelman,

Affiliation Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York, United States of America
⨯
Joseph M. Miano

* E-mail: j.m.miano@rochester.edu

Affiliations Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America, Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
⨯

Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Jeffrey W. Streb,
Xiaochun Long,
Ting-Hein Lee,
Qiang Sun,
Chad M. Kitchen,
Mary A. Georger,
Orazio J. Slivano,
William S. Blaner,
Daniel W. Carr,
Irwin H. Gelman

Published: April 5, 2011
https://doi.org/10.1371/journal.pone.0018538

Reader Comments

Post a new comment on this article

Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:07 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: University of Rochester Medical Centre
Title: “Multitasking Meds: Scientists Discover How Drug for Leukemia, Psoriasis, May Tackle Vascular Disease - News Room - University of Rochester Medical Center”
http://www.urmc.rochester...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Tumor suppressor genes
Is the Subject Area "Tumor suppressor genes" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Carotid arteries
Is the Subject Area "Carotid arteries" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Oils
Is the Subject Area "Oils" applicable to this article?

Thanks for your feedback.
PKA signaling cascade
Is the Subject Area "PKA signaling cascade" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.

Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Retinoid-Induced Expression and Activity of an Immediate Early Tumor Suppressor Gene in Vascular Smooth Muscle Cells

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:07 GMT