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Referee comments: Referee 1 (Michael A. Matthay)

Posted by PLOS_ONE_Group on 15 Feb 2008 at 19:02 GMT

Referee 1's review (Michael A. Matthay):

The authors have been very responsive to the comments and suggestions. The study is now of very high quality and breaks new ground.

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N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication the manuscript has been revised in light of these comments and to address other editorial requirements.