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Research Article

Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study

  • Ian W. Rodger mail,

    rodgeri@mcmaster.ca

    Affiliation: Department of Medicine, McMaster University, Hamilton, Ontario, Canada

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  • Dorothy Dilar,

    Affiliation: Diagnostic Imaging, St Joseph's Healthcare, Hamilton, Ontario, Canada

    X
  • Janet Dwyer,

    Affiliation: Diagnostic Imaging, St Joseph's Healthcare, Hamilton, Ontario, Canada

    X
  • John Bienenstock,

    Affiliations: Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada

    X
  • Andu Coret,

    Affiliation: Diagnostic Imaging, St Joseph's Healthcare, Hamilton, Ontario, Canada

    X
  • Judith Coret-Simon,

    Affiliation: Diagnostic Imaging, St Joseph's Healthcare, Hamilton, Ontario, Canada

    X
  • Gary Foster,

    Affiliation: Biostatistics, St Joseph's Healthcare, Hamilton, Ontario, Canada

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  • Arlene Franchetto,

    Affiliation: Diagnostic Imaging, Hamilton Health Sciences, Hamilton, Ontario, Canada

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  • Slobodan Franic,

    Affiliation: Diagnostic Imaging, St Joseph's Healthcare, Hamilton, Ontario, Canada

    X
  • Charles H. Goldsmith,

    Affiliation: Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada

    X
  • David Koff,

    Affiliation: Department of Radiology, McMaster University, Hamilton, Ontario, Canada

    X
  • Norman B. Konyer,

    Affiliation: Imaging Research Centre, St Joseph's Healthcare, Hamilton, Ontario, Canada

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  • Mitchell Levine,

    Affiliations: Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

    X
  • Ellen McDonald,

    Affiliation: Clinical Research, Hamilton Health Sciences, Hamilton, Ontario, Canada

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  • Michael D. Noseworthy,

    Affiliations: Department of Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada, Imaging Research Centre, St Joseph's Healthcare, Hamilton, Ontario, Canada

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  • John Paulseth,

    Affiliation: Department of Neurology, McMaster University, Hamilton, Ontario, Canada

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  • Luciana Ribeiro,

    Affiliation: Diagnostic Imaging, Hamilton Health Sciences, Hamilton, Ontario, Canada

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  • Mary Jane Sayles,

    Affiliation: Research Administration, St Joseph's Healthcare, Hamilton, Ontario, Canada

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  • Lehana Thabane

    Affiliation: Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

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  • Published: August 14, 2013
  • DOI: 10.1371/journal.pone.0072495

Reader Comments (3)

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Media coverage of this article

Posted by PLoS_ONE_Group on 16 Aug 2013 at 19:01 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: CTV News
Title: “No evidence of vein blockages related to CCSVI in MS patients, Canadian study says”
http://www.ctvnews.ca/hea...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

RE: Media coverage of this article

mangoflo replied to PLoS_ONE_Group on 22 Aug 2013 at 13:48 GMT

Media coverage of this article

PLoS_ONE_Group replied to mangoflo on 23 Aug 2013 at 18:15 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Macleans
Title: “Debunking the latest study ‘debunking’ CCSVI”
http://www2.macleans.ca/2...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

Media coverage of this article

PLoS_ONE_Group replied to PLoS_ONE_Group on 17 Sep 2013 at 16:06 GMT

The following articles represent some of the media coverage that has occurred for this paper:

Publication: CBC News
Title: “MS blocked vein theory disputed in Canadian study”
http://www.cbc.ca/news/he...

Publication: Globe and Mail
Title: “Canadian study casts doubt on Zamboni's 'liberation treatment' for MS”
http://www.theglobeandmai...

Publication: MedPage Today
Title: “Controversial MS Theory Flops Again”
http://www.medpagetoday.c...

Publication: TCTMD
Title: “Further Evidence Discredits Venous Hypothesis in Multiple Sclerosis”
http://www.tctmd.com/show...

Publication: The Spec.com
Title: “Patients have faith in MS theory despite findings of McMaster study”
http://www.thespec.com/ne...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff