A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

Aaron Mobley; Suzanne K. Linder; Russell Braeuer; Lee M. Ellis; Leonard Zwelling

doi:10.1371/journal.pone.0063221

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Research Article

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

Aaron Mobley,

Affiliation Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Suzanne K. Linder,

Affiliation Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Russell Braeuer,

Affiliation Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Lee M. Ellis ,

* E-mail: lellis@mdanderson.org (LME); lzwellin@mdanderson.org (LZ)

Affiliations Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Leonard Zwelling

* E-mail: lellis@mdanderson.org (LME); lzwellin@mdanderson.org (LZ)

Affiliation Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

Aaron Mobley,
Suzanne K. Linder,
Russell Braeuer,
Lee M. Ellis,
Leonard Zwelling

Published: May 15, 2013
https://doi.org/10.1371/journal.pone.0063221

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Kudos on doing and reporting this survey

Posted by JWoodgett on 27 May 2013 at 14:29 GMT

Hopefully, can be broadened to multiple institutions to help in reducing irreproducibility, encouraging trainees to stand up to poor practice and ensuring representative data. Data subversion/corruption serves no one, least of all the people paying for it.

No competing interests declared.

RE: Kudos on doing and reporting this survey

lellis replied to JWoodgett on 27 May 2013 at 20:57 GMT

Thanks the kind comment. We agree that this would be useful if the survey was conducted at other institutes. I would hope that PlosONE would be interested in publishing such a study. We would be very interesting in seeing such a study and would be happy to help in interpretation and comparison.

No competing interests declared.

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A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

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Kudos on doing and reporting this survey

Posted by JWoodgett on 27 May 2013 at 14:29 GMT

RE: Kudos on doing and reporting this survey

lellis replied to JWoodgett on 27 May 2013 at 20:57 GMT