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Research Article

Within-Host Evolution of Staphylococcus aureus during Asymptomatic Carriage

  • Tanya Golubchik equal contributor,

    equal contributor Contributed equally to this work with: Tanya Golubchik, Elizabeth M. Batty

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Elizabeth M. Batty equal contributor,

    equal contributor Contributed equally to this work with: Tanya Golubchik, Elizabeth M. Batty

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Ruth R. Miller,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

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  • Helen Farr,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

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  • Bernadette C. Young,

    Affiliation: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Hanna Larner-Svensson,

    Affiliations: National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Rowena Fung,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

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  • Heather Godwin,

    Affiliation: Oxford University Hospitals National Health Service Trust, Oxford, Oxfordshire, United Kingdom

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  • Kyle Knox,

    Affiliation: Department of Primary Care Health Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Antonina Votintseva,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

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  • Richard G. Everitt,

    Affiliation: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Teresa Street,

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Madeleine Cule,

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Camilla L. C. Ip,

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Xavier Didelot,

    Affiliation: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Timothy E. A. Peto,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

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  • Rosalind M. Harding,

    Affiliation: Department of Zoology, University of Oxford, Oxford, Oxfordshire, United Kingdom

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  • Daniel J. Wilson mail,

    daniel.wilson@ndm.ox.ac.uk (DJW); bowden@stats.ox.ac.uk (RB)

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom

    These authors also contributed equally to this work.

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  • Derrick W. Crook ,

    Affiliations: Experimental Medicine Division, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom

    These authors also contributed equally to this work.

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  • Rory Bowden mail

    daniel.wilson@ndm.ox.ac.uk (DJW); bowden@stats.ox.ac.uk (RB)

    Affiliations: Department of Statistics, University of Oxford, Oxford, Oxfordshire, United Kingdom, National Institute for Health Research Oxford Biomedical Research Centre, Oxford, Oxfordshire, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom

    These authors also contributed equally to this work.

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  • Published: May 01, 2013
  • DOI: 10.1371/journal.pone.0061319

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Media Coverage of This Article

Posted by PLoS_ONE_Group on 17 May 2013 at 22:54 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: EveryONE PLOS ONE Community Blog
Title: “Opportunistic pathogens evolve mostly harmlessly in healthy humans | EveryONE”
http://blogs.plos.org/eve...

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Competing interests declared: PLOS ONE Staff