Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

Huan-Chieh Chien; Hurng-Yi Wang; Yi-Ning Su; Kuan-Yu Lai; Li-Chen Lu; Pau-Chung Chen; Shih-Feng Tsai; Chung-I Wu; Wu-Shiun Hsieh; Che-Kun James Shen

doi:10.1371/journal.pone.0047481

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Peer-reviewed

Research Article

Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

Huan-Chieh Chien ,

Contributed equally to this work with: Huan-Chieh Chien, Hurng-Yi Wang, Yi-Ning Su

Affiliations Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan, Republic of China, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China
⨯
Hurng-Yi Wang ,

Contributed equally to this work with: Huan-Chieh Chien, Hurng-Yi Wang, Yi-Ning Su

Affiliation Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
⨯
Yi-Ning Su ,

Contributed equally to this work with: Huan-Chieh Chien, Hurng-Yi Wang, Yi-Ning Su

Affiliation Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan, Republic of China
⨯
Kuan-Yu Lai,

Affiliation Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China
⨯
Li-Chen Lu,

Affiliation Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China
⨯
Pau-Chung Chen,

Affiliation Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taipei, Taiwan, Republic of China
⨯
Shih-Feng Tsai,

Affiliation Division of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli County, Taiwan, Republic of China
⨯
Chung-I Wu,

Affiliation Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America
⨯
Wu-Shiun Hsieh,

Affiliation Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China
⨯
Che-Kun James Shen

* E-mail: ckshen@imb.sinica.edu.tw

Affiliations Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan, Republic of China, Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China
⨯

Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

Huan-Chieh Chien,
Hurng-Yi Wang,
Yi-Ning Su,
Kuan-Yu Lai,
Li-Chen Lu,
Pau-Chung Chen,
Shih-Feng Tsai,
Chung-I Wu,
Wu-Shiun Hsieh,
Che-Kun James Shen

Published: October 10, 2012
https://doi.org/10.1371/journal.pone.0047481

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Publisher's Note: Additional Corresponding Author

Posted by PLOS_ONE_Group on 25 Apr 2013 at 23:39 GMT

Author Wu-Shiun Hsieh should be an additional corresponding author, and can be contacted by the email address hsiehws@ntu.edu.tw

No competing interests declared.

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Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

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Publisher's Note: Additional Corresponding Author

Posted by PLOS_ONE_Group on 25 Apr 2013 at 23:39 GMT