Synergistic Actions of Hematopoietic and Mesenchymal Stem/Progenitor Cells in Vascularizing Bioengineered Tissues

Eduardo K. Moioli; Paul A. Clark; Mo Chen; James E. Dennis; Helaman P. Erickson; Stanton L. Gerson; Jeremy J. Mao

doi:10.1371/journal.pone.0003922

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Peer-reviewed

Research Article

Synergistic Actions of Hematopoietic and Mesenchymal Stem/Progenitor Cells in Vascularizing Bioengineered Tissues

Eduardo K. Moioli,

Affiliation Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, New York, New York, United States of America
⨯
Paul A. Clark,

Affiliation Department of Neurological Surgery CSC, University of Wisconsin at Madison Hospital, Madison, Wisconsin, United States of America
⨯
Mo Chen,

Affiliation Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, New York, New York, United States of America
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James E. Dennis,

Affiliation Department of Orthopaedics, Case Western Reserve University, Cleveland, Ohio, United States of America
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Helaman P. Erickson,

Affiliation Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, New York, New York, United States of America
⨯
Stanton L. Gerson,

Affiliation Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Jeremy J. Mao

* E-mail: jmao@columbia.edu

Affiliation Columbia University Medical Center, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, New York, New York, United States of America
⨯

Synergistic Actions of Hematopoietic and Mesenchymal Stem/Progenitor Cells in Vascularizing Bioengineered Tissues

Eduardo K. Moioli,
Paul A. Clark,
Mo Chen,
James E. Dennis,
Helaman P. Erickson,
Stanton L. Gerson,
Jeremy J. Mao

Published: December 15, 2008
https://doi.org/10.1371/journal.pone.0003922

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Citation

Posted by sheldonz on 13 Apr 2013 at 00:24 GMT

Bone marrow cells were isolated from whole marrow aspirates of the iliac crest of each of three healthy male donors (AllCells, http://www.allcells.com Berkeley, CA) and plated as in Fig. 1A. Human mesenchymal stem cells (MSC) were isolated per our previous methods using RosetteSep mesenchymal enrichment cocktail (StemCell Technologies, Vancouver, Canada) [33]

No competing interests declared.

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Cell differentiation
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Osteocalcin
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Synergistic Actions of Hematopoietic and Mesenchymal Stem/Progenitor Cells in Vascularizing Bioengineered Tissues

Synergistic Actions of Hematopoietic and Mesenchymal Stem/Progenitor Cells in Vascularizing Bioengineered Tissues

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Posted by sheldonz on 13 Apr 2013 at 00:24 GMT