Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

Jessica I. Gold; Jeffrey S. Martini; Jonathan Hullmann; Erhe Gao; J. Kurt Chuprun; Linda Lee; Douglas G. Tilley; Joseph E. Rabinowitz; Julie Bossuyt; Donald M. Bers; Walter J. Koch

doi:10.1371/journal.pone.0057324

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Peer-reviewed

Research Article

Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

Jessica I. Gold,

Affiliation Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Jeffrey S. Martini,

Affiliation Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Jonathan Hullmann,

Affiliation Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Erhe Gao,

Affiliation Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
J. Kurt Chuprun,

Affiliation Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Linda Lee,

Affiliation Department of Pharmacology, University of California Davis, Davis, California, United States of America
⨯
Douglas G. Tilley,

Affiliations Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Joseph E. Rabinowitz,

Affiliations Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Julie Bossuyt,

Affiliation Department of Pharmacology, University of California Davis, Davis, California, United States of America
⨯
Donald M. Bers,

Affiliation Department of Pharmacology, University of California Davis, Davis, California, United States of America
⨯
Walter J. Koch

* E-mail: Walter.Koch@temple.edu

Affiliations Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Center for Translational Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

Jessica I. Gold,
Jeffrey S. Martini,
Jonathan Hullmann,
Erhe Gao,
J. Kurt Chuprun,
Linda Lee,
Douglas G. Tilley,
Joseph E. Rabinowitz,
Julie Bossuyt,
Donald M. Bers

Published: March 5, 2013
https://doi.org/10.1371/journal.pone.0057324

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Posted by PLOS_ONE_Group on 09 Mar 2013 at 00:27 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Press Release
Title: “News & Announcements - Temple Health - Philadelphia, PA”
http://www.templehealth.o...[start_date]%20desc&major=4&inCtx5view=35

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Competing interests declared: PLOS ONE Staff

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Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 09 Mar 2013 at 00:27 GMT