Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

Xianlin Han; Steve Rozen; Stephen H. Boyle; Caroline Hellegers; Hua Cheng; James R. Burke; Kathleen A. Welsh-Bohmer; P. Murali Doraiswamy; Rima Kaddurah-Daouk

doi:10.1371/journal.pone.0021643

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Open Access

Peer-reviewed

Research Article

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

Xianlin Han,

Affiliation Sanford-Burnham Medical Research Institute, Orlando, Florida, United States of America
⨯
Steve Rozen,

Affiliation Department of Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore
⨯
Stephen H. Boyle,

Affiliation Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Caroline Hellegers,

Affiliation Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Hua Cheng,

Affiliation Sanford-Burnham Medical Research Institute, Orlando, Florida, United States of America
⨯
James R. Burke,

Affiliation Bryan Alzheimer Disease Research Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Kathleen A. Welsh-Bohmer,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Bryan Alzheimer Disease Research Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
P. Murali Doraiswamy,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Institute of Brain Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Rima Kaddurah-Daouk

* E-mail: kaddu001@mc.duke.edu

Affiliation Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

Xianlin Han,
Steve Rozen,
Stephen H. Boyle,
Caroline Hellegers,
Hua Cheng,
James R. Burke,
Kathleen A. Welsh-Bohmer,
P. Murali Doraiswamy,
Rima Kaddurah-Daouk

Published: July 11, 2011
https://doi.org/10.1371/journal.pone.0021643

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 29 Jul 2011 at 15:25 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Wall Street Journal
Title: “Dandruff Offers Clues to Disease - WSJ.com”
http://online.wsj.com/art...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 29 Jul 2011 at 15:25 GMT