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Research Article

Deep Sequencing of the Oral Microbiome Reveals Signatures of Periodontal Disease

  • Bo Liu equal contributor,

    equal contributor Contributed equally to this work with: Bo Liu, Lina L. Faller, Niels Klitgord, Varun Mazumdar

    Affiliations: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America, Department of Computer Science, University of Maryland, College Park, Maryland, United States of America

    X
  • Lina L. Faller equal contributor,

    equal contributor Contributed equally to this work with: Bo Liu, Lina L. Faller, Niels Klitgord, Varun Mazumdar

    Affiliation: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

    X
  • Niels Klitgord equal contributor,

    equal contributor Contributed equally to this work with: Bo Liu, Lina L. Faller, Niels Klitgord, Varun Mazumdar

    Affiliation: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

    X
  • Varun Mazumdar equal contributor,

    equal contributor Contributed equally to this work with: Bo Liu, Lina L. Faller, Niels Klitgord, Varun Mazumdar

    Affiliation: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

    X
  • Mohammad Ghodsi,

    Affiliations: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America, Department of Computer Science, University of Maryland, College Park, Maryland, United States of America

    X
  • Daniel D. Sommer,

    Affiliation: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

    X
  • Theodore R. Gibbons,

    Affiliations: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America, Biological Sciences Graduate Program, University of Maryland, College Park, Maryland, United States of America

    X
  • Todd J. Treangen,

    Affiliations: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America, The McKusick-Nathans Institute for Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Yi-Chien Chang,

    Affiliation: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

    X
  • Shan Li,

    Affiliation: Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • O. Colin Stine,

    Affiliation: Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Hatice Hasturk,

    Affiliation: The Forysth Institute, Department of Periodontology, Cambridge, Massachusetts, United States of America

    X
  • Simon Kasif,

    Affiliations: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America, Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America, Children’s Informatics Program, Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts, United States of America

    X
  • Daniel Segrè mail,

    dsegre@bu.edu (DS); mpop@umiacs.umd.edu (MP); samar@bu.edu (SA)

    Affiliations: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America, Department of Biology, Boston University, Boston, Massachusetts, United States of America, Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America

    X
  • Mihai Pop mail,

    dsegre@bu.edu (DS); mpop@umiacs.umd.edu (MP); samar@bu.edu (SA)

    Affiliations: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America, Department of Computer Science, University of Maryland, College Park, Maryland, United States of America, Biological Sciences Graduate Program, University of Maryland, College Park, Maryland, United States of America

    X
  • Salomon Amar mail

    dsegre@bu.edu (DS); mpop@umiacs.umd.edu (MP); samar@bu.edu (SA)

    Affiliations: Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America, Center for Anti-Inflammatory Therapeutics; Boston University Goldman School of Dental Medicine, Boston, Massachusetts, United States of America

    X
  • Published: June 04, 2012
  • DOI: 10.1371/journal.pone.0037919

Reader Comments (2)

Post a new comment on this article

sequence data public?

Posted by annaedlund on 09 Jan 2013 at 17:42 GMT

I am trying to find the novel TM7 sequence data that you have acquired but it is nowhere to be found? Is it not public? Thanks!

No competing interests declared.

RE: sequence data public?

mpop1 replied to annaedlund on 23 Jan 2013 at 08:50 GMT

I posted another comment, but just to have this as a response here as well - the data should soon show up in the NCBI project. In the meantime please contact me (mpop@umiacs.umd.edu) to obtain it.

No competing interests declared.