Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

Gale Smith; Rama Raghunandan; Yingyun Wu; Ye Liu; Michael Massare; Margret Nathan; Bin Zhou; Hanxin Lu; Sarathi Boddapati; Jingning Li; David Flyer; Gregory Glenn

doi:10.1371/journal.pone.0050852

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Open Access

Peer-reviewed

Research Article

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

Gale Smith ,

* E-mail: gsmith@novavax.com

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Rama Raghunandan,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Yingyun Wu,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Ye Liu,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Michael Massare,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Margret Nathan,

Affiliation Process Development, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Bin Zhou,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Hanxin Lu,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Sarathi Boddapati,

Affiliation Formulation Development, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Jingning Li,

Affiliation Analytical Development, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
David Flyer,

Affiliation Discovery, Novavax Incorporated, Rockville, Maryland, United States of America
⨯
Gregory Glenn

Affiliation Clinical Development, Novavax Incorporated, Rockville, Maryland, United States of America
⨯

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

Gale Smith,
Rama Raghunandan,
Yingyun Wu,
Ye Liu,
Michael Massare,
Margret Nathan,
Bin Zhou,
Hanxin Lu,
Sarathi Boddapati,
Jingning Li

Published: November 30, 2012
https://doi.org/10.1371/journal.pone.0050852

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Media Coverage of this Article

Posted by PLOS_ONE_Group on 07 Dec 2012 at 22:14 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Gazette
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http://www.gazette.net/ar...

Publication: MarketWatch
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http://www.marketwatch.co...

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Competing interests declared: PLOS ONE Staff

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Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

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Media Coverage of this Article

Posted by PLOS_ONE_Group on 07 Dec 2012 at 22:14 GMT