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Research Article

Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery

  • Peter S. Kutchukian,

    Affiliation: Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America

    X
  • Nadya Y. Vasilyeva,

    Affiliation: Department of Psychology, Northeastern University, Boston, Massachusetts, United States of America

    X
  • Jordan Xu,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

    X
  • Mika K. Lindvall,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

    X
  • Michael P. Dillon,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

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  • Meir Glick,

    Affiliation: Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America

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  • John D. Coley mail,

    j.coley@neu.edu (JDC); NBrooijmans@blueprintmedicines.com (NB)

    Affiliation: Department of Psychology, Northeastern University, Boston, Massachusetts, United States of America

    X
  • Natasja Brooijmans mail

    j.coley@neu.edu (JDC); NBrooijmans@blueprintmedicines.com (NB)

    Affiliation: Blueprint Medicines, Cambridge, Massachusetts, United States of America

    X
  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0048476

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Media Coverage of This Article

Posted by PLoS_ONE_Group on 30 Nov 2012 at 23:15 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Corante
Title: “How Do Chemist (Think That They) Judge Compounds?. In the Pipeline:”
http://pipeline.corante.c...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

RE: Media Coverage of This Article

PLoS_ONE_Group replied to PLoS_ONE_Group on 07 Dec 2012 at 22:05 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Chemistry World
Title: “Chemists cull compounds using intuition | Chemistry World”
http://www.rsc.org/chemis...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

RE: Media Coverage of This Article

Kutchukian replied to PLoS_ONE_Group on 14 Jan 2013 at 21:14 GMT

Publication: News@Northeastern
Title: "How chemists think"
http://www.northeastern.e...

Competing interests declared: Co-author

RE: RE: Media Coverage of This Article

PLoS_ONE_Group replied to Kutchukian on 18 Jan 2013 at 23:17 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: news @ Northeastern
Title: “How chemists think | news @ Northeastern”
http://www.northeastern.e...

Publication: The Guardian
Title: “Can genetics help explain why some policies only work on some people? | Jason Fletcher | Science | guardian.co.uk”
http://www.guardian.co.uk...

Publication: Yale News
Title: “YaleNews | It' s genetic: Some smokers have biological resistance to anti-tobacco policies”
http://news.yale.edu/2012...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff