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Research Article

Human Cells Display Reduced Apoptotic Function Relative to Chimpanzee Cells

  • Gaurav Arora equal contributor,

    equal contributor Contributed equally to this work with: Gaurav Arora, Roman Mezencev

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  • Roman Mezencev equal contributor,

    equal contributor Contributed equally to this work with: Gaurav Arora, Roman Mezencev

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  • John F. McDonald mail

    john.mcdonald@biology.gatech.edu

    Affiliation: School of Biology and Parker H. Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America

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  • Published: September 28, 2012
  • DOI: 10.1371/journal.pone.0046182

Reader Comments (2)

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Cancer & Brains

Posted by caldararo on 18 Oct 2012 at 17:35 GMT

The researchers should look at the other big brained vertebrates like dolphins to see if there is validity to their thesis. Cancer rates in vertebrates vary significantly, even dinosaurs had cancer and given our sample of surviving fossils, the rate must have been quite high. Projecting from apoptosis to cancer rates is a bit of a jump unless there is a mechanism, e.g., exosome failure.

No competing interests declared.