BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”?

Andrea Weghofer; Muy-Kheng Tea; David H. Barad; Ann Kim; Christian F. Singer; Klaus Wagner; Norbert Gleicher

doi:10.1371/journal.pone.0044753

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Research Article

BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”?

Andrea Weghofer,

Affiliations The Center for Human Reproduction, New York, New York, United States of America, Department of Gynecological Endocrinology and Reproductive Medicine, Medical University Vienna, Vienna, Austria
⨯
Muy-Kheng Tea,

Affiliation Department of Obstetrics and Gynecology, Medical University Vienna, Vienna, Austria
⨯
David H. Barad,

Affiliations The Center for Human Reproduction, New York, New York, United States of America, Foundation for Reproductive Medicine, New York, New York, United States of America
⨯
Ann Kim,

Affiliation The Center for Human Reproduction, New York, New York, United States of America
⨯
Christian F. Singer,

Affiliation Department of Obstetrics and Gynecology, Medical University Vienna, Vienna, Austria
⨯
Klaus Wagner,

Affiliation Department of Human Genetics, Medical University Graz, Graz, Austria
⨯
Norbert Gleicher

* E-mail: ngleicher@thechr.com

Affiliations The Center for Human Reproduction, New York, New York, United States of America, Foundation for Reproductive Medicine, New York, New York, United States of America
⨯

BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”?

Andrea Weghofer,
Muy-Kheng Tea,
David H. Barad,
Ann Kim,
Christian F. Singer,
Klaus Wagner,
Norbert Gleicher

Published: September 12, 2012
https://doi.org/10.1371/journal.pone.0044753

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Publisher's Note: Correction from the Authors

Posted by NorbertGleicherMD on 04 Oct 2012 at 19:21 GMT

Authors have a correction in the Author Contributions section, as follows: Drs. Weghofer, Tea, Barad and Gleicher contributed equally to the manuscript.

No competing interests declared.

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BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”?

BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”?

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Publisher's Note: Correction from the Authors

Posted by NorbertGleicherMD on 04 Oct 2012 at 19:21 GMT