A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

Kjersti Aagaard; Kevin Riehle; Jun Ma; Nicola Segata; Toni-Ann Mistretta; Cristian Coarfa; Sabeen Raza; Sean Rosenbaum; Ignatia Van den Veyver; Aleksandar Milosavljevic; Dirk Gevers; Curtis Huttenhower; Joseph Petrosino; James Versalovic

doi:10.1371/journal.pone.0036466

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Peer-reviewed

Research Article

A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

Kjersti Aagaard ,

* E-mail: aagaardt@bcm.edu

Affiliations Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America, Bioinformatics Research Laboratory, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Kevin Riehle,

Affiliation Bioinformatics Research Laboratory, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Jun Ma,

Affiliations Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America, Bioinformatics Research Laboratory, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Nicola Segata,

Affiliation Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Toni-Ann Mistretta,

Affiliation Department of Pathology & Immunology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Cristian Coarfa,

Affiliation Bioinformatics Research Laboratory, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Sabeen Raza,

Affiliation Department of Pathology & Immunology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Sean Rosenbaum,

Affiliation Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Ignatia Van den Veyver,

Affiliation Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Aleksandar Milosavljevic,

Affiliation Bioinformatics Research Laboratory, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
Dirk Gevers,

Affiliation Broad Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Curtis Huttenhower,

Affiliation Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Joseph Petrosino,

Affiliation Department of Molecular Virology and Microbiology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯
James Versalovic

Affiliation Department of Pathology & Immunology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, United States of America
⨯

A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

Kjersti Aagaard,
Kevin Riehle,
Jun Ma,
Nicola Segata,
Toni-Ann Mistretta,
Cristian Coarfa,
Sabeen Raza,
Sean Rosenbaum,
Ignatia Van den Veyver,
Aleksandar Milosavljevic

Published: June 13, 2012
https://doi.org/10.1371/journal.pone.0036466

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Article Data Link

Posted by PLOS_ONE_Group on 02 Oct 2012 at 13:39 GMT

The data for this article have been deposited at SRA and are available under the accession number SRA056340

Competing interests declared: PLOS ONE Staff

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A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

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Article Data Link

Posted by PLOS_ONE_Group on 02 Oct 2012 at 13:39 GMT