Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

Eleonora Napoli; Catherine Ross-Inta; Sarah Wong; Connie Hung; Yasuko Fujisawa; Danielle Sakaguchi; James Angelastro; Alicja Omanska-Klusek; Robert Schoenfeld; Cecilia Giulivi

doi:10.1371/journal.pone.0042504

Loading metrics

Open Access

Peer-reviewed

Research Article

Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

Eleonora Napoli,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Catherine Ross-Inta,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Sarah Wong,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Connie Hung,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Yasuko Fujisawa,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Danielle Sakaguchi,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
James Angelastro,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Alicja Omanska-Klusek,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Robert Schoenfeld,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America
⨯
Cecilia Giulivi

* E-mail: cgiulivi@ucdavis.edu

Affiliations Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America, Medical Investigations of Neurodevelopmental Disorders Institute, School of Medicine, University of California Davis, Davis, California, United States of America
⨯

Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

Eleonora Napoli,
Catherine Ross-Inta,
Sarah Wong,
Connie Hung,
Yasuko Fujisawa,
Danielle Sakaguchi,
James Angelastro,
Alicja Omanska-Klusek,
Robert Schoenfeld,
Cecilia Giulivi

Published: August 10, 2012
https://doi.org/10.1371/journal.pone.0042504

Reader Comments

Post a new comment on this article

Media Coverage of This Article

Posted by PLOS_ONE_Group on 17 Aug 2012 at 23:23 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: NetDoctor.co.uk
Title: “Health News - Study reveals role of gene defect in autism behaviour”
http://www.netdoctor.co.u...

Publication: Psych Central
Title: “Gene Related to Autism Behavior ID'd in Mice Study | Psych Central News”
http://psychcentral.com/n...

Publication: UC Davis Health System
Title: “Research shows gene defect's role in autism-like behavior”
http://www.ucdmc.ucdavis....

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mitochondrial DNA
Is the Subject Area "Mitochondrial DNA" applicable to this article?

Thanks for your feedback.
Mice
Is the Subject Area "Mice" applicable to this article?

Thanks for your feedback.
Cerebellum
Is the Subject Area "Cerebellum" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Animal behavior
Is the Subject Area "Animal behavior" applicable to this article?

Thanks for your feedback.
Protein expression
Is the Subject Area "Protein expression" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.

Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Media Coverage of This Article

Posted by PLOS_ONE_Group on 17 Aug 2012 at 23:23 GMT