A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

Jean Mukherjee; Jacqueline M. Tremblay; Clinton E. Leysath; Kwasi Ofori; Karen Baldwin; Xiaochuan Feng; Daniela Bedenice; Robert P. Webb; Patrick M. Wright; Leonard A. Smith; Saul Tzipori; Charles B. Shoemaker

doi:10.1371/journal.pone.0029941

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Peer-reviewed

Research Article

A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

Jean Mukherjee ,

Contributed equally to this work with: Jean Mukherjee, Jacqueline M. Tremblay

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Jacqueline M. Tremblay ,

Contributed equally to this work with: Jean Mukherjee, Jacqueline M. Tremblay

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Clinton E. Leysath,

Affiliation National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kwasi Ofori,

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Karen Baldwin,

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Xiaochuan Feng,

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Daniela Bedenice,

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Robert P. Webb,

Affiliation United States Army Medical Research Institute for Infectious Diseases, Frederick, Maryland, United States of America
⨯
Patrick M. Wright,

Affiliation United States Army Medical Research Institute for Infectious Diseases, Frederick, Maryland, United States of America
⨯
Leonard A. Smith,

Affiliation United States Army Medical Research Institute for Infectious Diseases, Frederick, Maryland, United States of America
⨯
Saul Tzipori,

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯
Charles B. Shoemaker

* E-mail: charles.shoemaker@tufts.edu

Affiliation Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, United States of America
⨯

A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

Jean Mukherjee,
Jacqueline M. Tremblay,
Clinton E. Leysath,
Kwasi Ofori,
Karen Baldwin,
Xiaochuan Feng,
Daniela Bedenice,
Robert P. Webb,
Patrick M. Wright,
Leonard A. Smith

Published: January 6, 2012
https://doi.org/10.1371/journal.pone.0029941

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 22 Jun 2012 at 23:37 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Newswise
Title: “Antitoxin Strategy May Help Target Other Pathogens”
http://www.newswise.com/a...

Publication: Tufts University
Title: “"Beads on a String" Approach Represents Novel Way of Fighting Toxins | Tufts Now”
http://now.tufts.edu/news...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 22 Jun 2012 at 23:37 GMT