Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

Jingqiu Chen; Daniel Korostyshevsky; Sean Lee; Ethan O. Perlstein

doi:10.1371/journal.pone.0034024

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Open Access

Peer-reviewed

Research Article

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

Jingqiu Chen ,

Contributed equally to this work with: Jingqiu Chen, Daniel Korostyshevsky

Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
⨯
Daniel Korostyshevsky ,

Contributed equally to this work with: Jingqiu Chen, Daniel Korostyshevsky

Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
⨯
Sean Lee,

Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
⨯
Ethan O. Perlstein

* E-mail: eperlste@princeton.edu

Affiliation Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
⨯

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

Jingqiu Chen,
Daniel Korostyshevsky,
Sean Lee,
Ethan O. Perlstein

Published: April 18, 2012
https://doi.org/10.1371/journal.pone.0034024

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Interesting paper

Posted by BryanRoth on 10 May 2012 at 16:33 GMT

This is an interesting paper which provides new insights into potential novel targets of antidepressant drug action using yeast as a model system.

Highly recommended!

No competing interests declared.

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Cell membranes
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Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy

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Interesting paper

Posted by BryanRoth on 10 May 2012 at 16:33 GMT