Ets-1 Confers Cranial Features on Neural Crest Delamination

Eric Théveneau; Jean-Loup Duband; Muriel Altabef

doi:10.1371/journal.pone.0001142

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Research Article

Ets-1 Confers Cranial Features on Neural Crest Delamination

Eric Théveneau,

Current address: Department of Anatomy and Developmental Biology, University College London, London, United Kingdom

Affiliations Université Pierre et Marie Curie - Paris6, UMR 7622, Laboratoire de Biologie du Développement, Paris, France, CNRS, UMR 7622 Laboratoire de Biologie du Développement, Paris, France
⨯
Jean-Loup Duband,

Affiliations Université Pierre et Marie Curie - Paris6, UMR 7622, Laboratoire de Biologie du Développement, Paris, France, CNRS, UMR 7622 Laboratoire de Biologie du Développement, Paris, France
⨯
Muriel Altabef

*To whom correspondence should be addressed. E-mail: Muriel.Altabef@snv.jussieu.fr

Affiliations Université Pierre et Marie Curie - Paris6, UMR 7622, Laboratoire de Biologie du Développement, Paris, France, CNRS, UMR 7622 Laboratoire de Biologie du Développement, Paris, France
⨯

Ets-1 Confers Cranial Features on Neural Crest Delamination

Eric Théveneau,
Jean-Loup Duband,
Muriel Altabef

Published: November 7, 2007
https://doi.org/10.1371/journal.pone.0001142

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Uncovering the basis of cephalic neural crest delamination…

Posted by LilianaOsorio on 09 Nov 2007 at 14:55 GMT

The existence of significant differences in the delamination of neural crest cells in cranial as compared to trunk level of the axis has been considered before. However, no data was available concerning the mechanisms leading to these differences. Now with this work, we start to get insight about these mechanisms and to uncover the basis of the characteristic neural crest cell delamination at cephalic levels. Moreover, it constitutes a great example of how neural crest fate and neural crest delamination are independent processes. To finish, I would like to congratulate the author for doing all these beautiful illustrations.

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Synthesis phase
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Electroporation
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DAPI staining
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Neural crest
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Transfection
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In situ hybridization
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Gene expression
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Ets-1 Confers Cranial Features on Neural Crest Delamination

Ets-1 Confers Cranial Features on Neural Crest Delamination

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Uncovering the basis of cephalic neural crest delamination…

Posted by LilianaOsorio on 09 Nov 2007 at 14:55 GMT