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Research Article

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

  • Otto Erlwein,

    Affiliation: Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom

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  • Steve Kaye,

    Affiliation: Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom

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  • Myra O. McClure mail,

    m.mcclure@imperial.ac.uk

    Affiliation: Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom

    X
  • Jonathan Weber,

    Affiliation: Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom

    X
  • Gillian Wills,

    Affiliation: Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom

    X
  • David Collier,

    Affiliation: Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry (King's College London) De Crespigny Park, Denmark Hill, London, United Kingdom

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  • Simon Wessely,

    Affiliation: Department of Psychological Medicine, Institute of Psychiatry, King's College London, Camberwell, London, United Kingdom

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  • Anthony Cleare

    Affiliation: Department of Psychological Medicine, Institute of Psychiatry, King's College London, Camberwell, London, United Kingdom

    X
  • Published: January 06, 2010
  • DOI: 10.1371/journal.pone.0008519

Reader Comments (31)

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Posted by Science-Based on 07 Jan 2010 at 05:03 GMT

Completely different cohort studied. NOT a replication study. This study did NOT use the rigorous Canadian AND Fukuda criteria for cohort selection, used in the esteemed Science paper. Therefore this paper cannot claim to be a replication study, as it was investigating an entirely different patient population. PLOS should know better. The results reflect an apples-and-oranges comparison.
Link to Canadian Criteria: http://www.cfids-cab.org/...

No competing interests declared.