Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

Otto Erlwein; Steve Kaye; Myra O. McClure; Jonathan Weber; Gillian Wills; David Collier; Simon Wessely; Anthony Cleare

doi:10.1371/journal.pone.0008519

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Peer-reviewed

Research Article

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

Otto Erlwein,

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom
⨯
Steve Kaye,

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom
⨯
Myra O. McClure ,

* E-mail: m.mcclure@imperial.ac.uk

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom
⨯
Jonathan Weber,

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom
⨯
Gillian Wills,

Affiliation Jefferiss Research Trust Laboratories, Section of Infectious Diseases, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, United Kingdom
⨯
David Collier,

Affiliation Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry (King's College London) De Crespigny Park, Denmark Hill, London, United Kingdom
⨯
Simon Wessely,

Affiliation Department of Psychological Medicine, Institute of Psychiatry, King's College London, Camberwell, London, United Kingdom
⨯
Anthony Cleare

Affiliation Department of Psychological Medicine, Institute of Psychiatry, King's College London, Camberwell, London, United Kingdom
⨯

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

Otto Erlwein,
Steve Kaye,
Myra O. McClure,
Jonathan Weber,
Gillian Wills,
David Collier,
Simon Wessely,
Anthony Cleare

Published: January 6, 2010
https://doi.org/10.1371/journal.pone.0008519

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Posted by Science-Based on 07 Jan 2010 at 05:03 GMT

Completely different cohort studied. NOT a replication study. This study did NOT use the rigorous Canadian AND Fukuda criteria for cohort selection, used in the esteemed Science paper. Therefore this paper cannot claim to be a replication study, as it was investigating an entirely different patient population. PLOS should know better. The results reflect an apples-and-oranges comparison.
Link to Canadian Criteria: http://www.cfids-cab.org/...

No competing interests declared.

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Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

Failure to Detect the Novel Retrovirus XMRV in Chronic Fatigue Syndrome

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Posted by Science-Based on 07 Jan 2010 at 05:03 GMT