Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms

Enrique Balleza; Elena R. Alvarez-Buylla; Alvaro Chaos; Stuart Kauffman; Ilya Shmulevich; Maximino Aldana

doi:10.1371/journal.pone.0002456

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Research Article

Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms

Enrique Balleza,

Affiliation Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Elena R. Alvarez-Buylla,

Affiliation Instituto de Ecología, Universidad Nacional Autónoma de México, San Nicolás de Los Garza, México
⨯
Alvaro Chaos,

Affiliation Instituto de Ecología, Universidad Nacional Autónoma de México, San Nicolás de Los Garza, México
⨯
Stuart Kauffman,

Affiliation Institute of Biocomplexity and Informatics, University of Calgary, Calgary, Alberta, Canada
⨯
Ilya Shmulevich,

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America
⨯
Maximino Aldana

* E-mail: max@fis.unam.mx

Affiliation Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯

Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms

Enrique Balleza,
Elena R. Alvarez-Buylla,
Alvaro Chaos,
Stuart Kauffman,
Ilya Shmulevich,
Maximino Aldana

Published: June 18, 2008
https://doi.org/10.1371/journal.pone.0002456

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Experimental evidence of 40 year old model

Posted by carlos on 25 Feb 2009 at 23:35 GMT

People have been using RBNs as models of genetic regulatory networks for 40 years. Kauffman made his hypothesis about "life at the edge of chaos" around 15 years ago. This article shows convincing evidence for Kauffman's hypothesis.

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Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms

Critical Dynamics in Genetic Regulatory Networks: Examples from Four Kingdoms

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Experimental evidence of 40 year old model

Posted by carlos on 25 Feb 2009 at 23:35 GMT