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Research Article

Human Natural Killer T Cells Are Heterogeneous in Their Capacity to Reprogram Their Effector Functions

  • Karla A. Eger,

    Affiliation: Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Mark S. Sundrud,

    Affiliation: Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    Current address: CBR Institute for Biomedical Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Alison A. Motsinger,

    Affiliation: Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Michelle Tseng,

    Affiliation: Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    Current address: Department of Microbiology, New York University School of Medicine, New York, New York, United States of America

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  • Luc Van Kaer,

    Affiliation: Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Derya Unutmaz mail

    To whom correspondence should be addressed. E-mail: Derya.Unutmaz@med.nyu.edu

    Affiliation: Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    Current address: Department of Microbiology, New York University School of Medicine, New York, New York, United States of America

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  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000050

Reader Comments (10)

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Definition of NKT cells

Posted by Derya on 10 Feb 2007 at 23:34 GMT

Natural killer T
http://plosone.org/article/info:doi/10.1371/journal.pone.0000050#article1.front1.article-meta1.abstract1.sec1.p1

In the past NKT cells have been referred to a heteregenous group of T cells with NK markers. More recently NKT cell typically denote CD1d-restricted T cells, also called invariant NKT cells (iNKT cells). For more info on NKT cell classification see this wiki page: http://www.nkcells.info/wiki/index.php/NKT_cell