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Research Article

At-Risk and Recent-Onset Type 1 Diabetic Subjects Have Increased Apoptosis in the CD4+CD25+high T-Cell Fraction

  • Sanja Glisic-Milosavljevic,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Jill Waukau,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Parthav Jailwala,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Srikanta Jana,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Huoy-Jii Khoo,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Hope Albertz,

    Affiliation: Blood Center of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Jeffrey Woodliff,

    Affiliation: Flow Cytometry Core Facility, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Marilyn Koppen,

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Ramin Alemzadeh,

    Affiliation: Children's Hospital of Wisconsin Diabetes Center, Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • William Hagopian,

    Affiliation: Pacific Northwest Research Institute, Seattle, Washington, United States of America

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  • Soumitra Ghosh mail

    To whom correspondence should be addressed. E-mail: sghosh@mcw.edu

    Affiliation: The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America

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  • Published: January 03, 2007
  • DOI: 10.1371/journal.pone.0000146

Reader Comments (1)

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good & novel study on T-cell apoptosis

Posted by kmaedler on 10 Jul 2007 at 17:01 GMT