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Research Article

A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice

  • Jamie L. Barger,

    Affiliation: LifeGen Technologies, LLC, Madison, Wisconsin, United States of America

    X
  • Tsuyoshi Kayo,

    Affiliation: LifeGen Technologies, LLC, Madison, Wisconsin, United States of America

    X
  • James M. Vann,

    Affiliations: Department of Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America, Department of Genetics, University of Wisconsin, Madison, Wisconsin, United States of America

    X
  • Edward B. Arias,

    Affiliation: Division of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Jelai Wang,

    Affiliation: Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Timothy A. Hacker,

    Affiliation: Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Ying Wang,

    Affiliation: R&D Human Nutrition and Health, DSM Nutritional Products Ltd., Basel, Switzerland

    X
  • Daniel Raederstorff,

    Affiliation: R&D Human Nutrition and Health, DSM Nutritional Products Ltd., Basel, Switzerland

    X
  • Jason D. Morrow,

    Affiliations: Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    X
  • Christiaan Leeuwenburgh,

    Affiliation: Department of Aging and Geriatrics and College of Medicine, University of Florida, Gainesville, Florida, United States of America

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  • David B. Allison,

    Affiliation: Section on Statistical Genetics, Department of Biostatistics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

    X
  • Kurt W. Saupe,

    Affiliation: Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Gregory D. Cartee,

    Affiliation: Division of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America

    X
  • Richard Weindruch mail,

    rhweindr@wisc.edu (RW); taprolla@wisc.edu (TP)

    Affiliation: Department of Medicine and Veterans Administration Hospital, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Tomas A. Prolla mail

    rhweindr@wisc.edu (RW); taprolla@wisc.edu (TP)

    Affiliations: Department of Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America, Department of Genetics, University of Wisconsin, Madison, Wisconsin, United States of America

    X
  • Published: June 04, 2008
  • DOI: 10.1371/journal.pone.0002264

Reader Comments (5)

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excellent work

Posted by hblal on 05 Jun 2008 at 03:27 GMT

written clearly, timely and relevant research