Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel; Adam E. Sienkiewicz; Renata Picciani; Richard K. Lee; Sanjoy K. Bhattacharya

doi:10.1371/journal.pone.0023070

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Peer-reviewed

Research Article

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Adam E. Sienkiewicz,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Renata Picciani,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Richard K. Lee,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Sanjoy K. Bhattacharya

* E-mail: Sbhattacharya@med.miami.edu

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel,
Adam E. Sienkiewicz,
Renata Picciani,
Richard K. Lee,
Sanjoy K. Bhattacharya

Published: August 23, 2011
https://doi.org/10.1371/journal.pone.0023070

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Posted by ritobrata on 30 Aug 2011 at 12:08 GMT

A mechanistic insight into how one specific secreted protein (Cochlin) in extracellular matrix interacts with other proteins thereby affecting the structure of trabecular meshwork during fluid flow changes.

No competing interests declared.

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Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

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Posted by ritobrata on 30 Aug 2011 at 12:08 GMT