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Research Article

Strong HIV-1-Specific T Cell Responses in HIV-1-Exposed Uninfected Infants and Neonates Revealed after Regulatory T Cell Removal

  • Fatema A. Legrand,

    Affiliation: Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America

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  • Douglas F. Nixon mail,

    To whom correspondence should be addressed. E-mail: douglas.nixon@ucsf.edu

    Affiliation: Division of Experimental Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Christopher P. Loo,

    Affiliation: Division of Experimental Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Erika Ono,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Joan M. Chapman,

    Affiliation: Division of Experimental Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Maristela Miyamoto,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Ricardo S. Diaz,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Amélia M.N. Santos,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Regina C.M. Succi,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Jacob Abadi,

    Affiliation: Jacobi Medical Center, Albert Einstein School of Medicine, Bronx, New York, United States of America

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  • Michael G. Rosenberg,

    Affiliation: Jacobi Medical Center, Albert Einstein School of Medicine, Bronx, New York, United States of America

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  • Maria Isabel de Moraes-Pinto,

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Esper G. Kallas

    Affiliation: Federal University of São Paulo, São Paulo, Brazil

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  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000102

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Phenotype marker of Tregs

Posted by ekallas on 28 Jan 2007 at 03:07 GMT

CD4+CD25+CD127−
http://plosone.org/article/info:doi/10.1371/journal.pone.0000102#article1.front1.article-meta1.abstract1.sec2.p1

Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA.
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
J Exp Med. 2006 Jul 10;203(7):1701-11