Common Variation in ISL1 Confers Genetic Susceptibility for Human Congenital Heart Disease

• Kristen N. Stevens,

  Affiliation Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Hakon Hakonarson,

  Affiliation The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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• Cecilia E. Kim,

  Affiliation The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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• Pieter A. Doevendans,

  Affiliation Department of Cardiology, UMC Utrecht, Utrecht, The Netherlands

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• Bobby P. C. Koeleman,

  Affiliation Department of Medical Genetics, UMC Utrecht, Utrecht, The Netherlands

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• Seema Mital,

  Affiliation Heart Center, Hospital for Sick Children, Toronto, Ontario, Canada

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• Jennifer Raue,

  Affiliation The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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• Joseph T. Glessner,

  Affiliation The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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• John G. Coles,

  Affiliation Heart Center, Hospital for Sick Children, Toronto, Ontario, Canada

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• Victor Moreno,

  Affiliation Biostatistics and Bioinformatics Unit, IDIBELL-Catalan Institute of Oncology and University of Barcelona, L'Hospitalet del Llobregat, Barcelona, Spain

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• Anne Granger,

  Affiliation The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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• Stephen B. Gruber ,

  * E-mail: sgruber@umich.edu (SBG); pgruber@mail.med.upenn.edu (PJG)

  Affiliations Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

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• Peter J. Gruber

  * E-mail: sgruber@umich.edu (SBG); pgruber@mail.med.upenn.edu (PJG)

  Affiliations The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Institute for Regenerative Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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