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A question about false memories

Posted by Margaret1 on 19 Nov 2008 at 07:50 GMT

Dear Professor Kiekelmann,

I am a student from Taiwan and interested in memory. I have read your paper entitle "Sleep loss produces false memories." That is very interesting paper and enlighten me on the issue. It presented conscientious and careful design and illustrated reasonable outcome. I really enjoy reading this article.
However, I have a question about the decision of delay between learning and retrieval testing. According to the paper, the factor "sleep or wakefulness after learning" was manipulated in exp.3. I wondered that why this experiment set retrieval test at 3rd day evening but not at 3rd day morning? It seem equally manipulate the factor and more reasonable to compare the result of exp.2 and exp.3 in that way. Furthermore, what is the reasons to decided use 9, 33, or 44 hours interval between learning and retrieval testing? Could you kindly explain your considerations or give me some references about this question?
Thank you for reading my email. I am really appreciated your time.

Best regard,

Margaret

RE: A question about false memories

Diekelmann replied to Margaret1 on 21 Nov 2008 at 13:05 GMT

Dear Margaret,

Thank you very much for your interest in our work and for raising this issue. Concerning your first question, Exp. 2 and 3 were separate control experiments for Exp. 1, with different aspects being manipulated and we did not intend to directly compare these experiments. In Exp. 2 we aimed at showing that sleep deprivation at retrieval (also during the second night) enhances false memories. Retrieval testing took place in the morning so that the length of sleep deprivation was comparable to Exp. 1 (24 h). Exp. 3 was designed to manipulate sleep vs. wakefulness after learning without the confounding factors sleep deprivation at retrieval and circadian variation. Exp. 1 showed that the sleep group and day wake group did not differ in false memory rate. However, these two groups differed substantially with respect to circadian factors: encoding, consolidation and retrieval occurred during different circadian phases and circadian factors are known to have substantial impact on cognitive processing (e.g., Schmidt et al, 2007, Cogn Neuropsychol, 24(7), 755-789). To control for circadian variations we wanted to introduce learning and retrieval during the same circadian phase in Exp. 3 and therefore retrieval testing was shifted to 18:30. In this way, groups were not only comparable for encoding, consolidation and retrieval times but even within subjects, encoding and retrieval took place in the same circadian phase.
We further established a retention interval of 9 and 33 hours due to considerations concerning learning and retrieval times in the sleep groups. We wanted learning to take place immediately before sleep, subjects should sleep for 8 hours and retrieval testing should be done half an hour after awakening. In Exp. 3 retrieval testing was postponed to the evening phase as mentioned above, resulting in a 44 hours retention interval.

I hope this helped clarifying the issue.

All the best,

Susanne