Advertisement
Research Article

Self-Correcting Maps of Molecular Pathways

  • Andrey Rzhetsky equal contributor mail,

    equal contributor Contributed equally to this work with: Andrey Rzhetsky, Tian Zheng, Chani Weinreb

    To whom correspondence should be addressed. E-mail: andrey.rzhetsky@dbmi.columbia.edu

    Affiliations: Department of Biomedical Informatics, Center for Computational Biology and Bioinformatics and Joint Centers for Systems Biology, Columbia University, New York, New York, United States of America, Judith P. Sulzberger MD Columbia Genome Center and Department of Biology, Columbia University, New York, New York, United States of America

    X
  • Tian Zheng equal contributor,

    equal contributor Contributed equally to this work with: Andrey Rzhetsky, Tian Zheng, Chani Weinreb

    Affiliation: Department of Statistics, Columbia University, New York, New York, United States of America

    X
  • Chani Weinreb equal contributor

    equal contributor Contributed equally to this work with: Andrey Rzhetsky, Tian Zheng, Chani Weinreb

    Affiliation: Department of Biomedical Informatics, Center for Computational Biology and Bioinformatics and Joint Centers for Systems Biology, Columbia University, New York, New York, United States of America

    X
  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000061

Reader Comments (2)

Post a new comment on this article

Generalizable method

Posted by dsingh on 09 Jan 2007 at 21:20 GMT

Our approach can be directly applied to an array of diverse problems including those encountered in molecular biology, ecology, economics, politics, and sociology.
http://plosone.org/article/info:doi/10.1371/journal.pone.0000061#article1.front1.article-meta1.abstract1.p1

The possibility of applying such a method to data heavy problems is quite fascinating. I am particularly interested in seeing if one can feed the method a large data set and see what kind of predictions can be made, either from disparate omics data or from business data