Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

Dominick J. Laddy; Jian Yan; Michele Kutzler; Darwyn Kobasa; Gary P. Kobinger; Amir S. Khan; Jack Greenhouse; Niranjan Y. Sardesai; Ruxandra Draghia-Akli; David B. Weiner

doi:10.1371/journal.pone.0002517

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Peer-reviewed

Research Article

Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

Dominick J. Laddy,

Affiliation Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Jian Yan,

Affiliation Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Michele Kutzler,

Affiliation Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Darwyn Kobasa,

Affiliation Respiratory Viruses, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
⨯
Gary P. Kobinger,

Affiliations Special Pathogens, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
⨯
Amir S. Khan,

Affiliation VGX Pharmaceuticals, Blue Bell, Pennsylvania, United States of America
⨯
Jack Greenhouse,

Affiliation Bioqual, Inc., Rockville, Maryland, United States of America
⨯
Niranjan Y. Sardesai,

Affiliation VGX Pharmaceuticals, Blue Bell, Pennsylvania, United States of America
⨯
Ruxandra Draghia-Akli,

Affiliation VGX Pharmaceuticals, Blue Bell, Pennsylvania, United States of America
⨯
David B. Weiner

* E-mail: dbweiner@mail.med.upenn.edu

Affiliation Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

Dominick J. Laddy,
Jian Yan,
Michele Kutzler,
Darwyn Kobasa,
Gary P. Kobinger,
Amir S. Khan,
Jack Greenhouse,
Niranjan Y. Sardesai,
Ruxandra Draghia-Akli,
David B. Weiner

Published: June 25, 2008
https://doi.org/10.1371/journal.pone.0002517

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Publisher's Note: Correction to Acknowledgments

Posted by PLOS_ONE_Group on 01 Jul 2008 at 19:30 GMT

The viruses used for the HI assay are reassortant strains obtained from Dr. Rubin Donis (CDC, Atlanta, GA).
http://plosone.org/article/info:doi/10.1371/journal.pone.0002517#article1.back1.ack1.p1

The authors would also like to acknowledge Hanne Anderson (Bioqual, Inc) for her help in this study.

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Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

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Publisher's Note: Correction to Acknowledgments

Posted by PLOS_ONE_Group on 01 Jul 2008 at 19:30 GMT