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Cells with a cardiogenic potential

Posted by aumezawa on 14 Jun 2008 at 09:39 GMT

Among the 30 groups, 21 groups included cells with a cardiomyogenic potential (Fig. 1B: red numbers).
http://plosone.org/article/info:doi/10.1371/journal.pone.0002407#article1.body1.sec2.sec1.p1

We do not, of course, think that all categorized cells are of cardiomyogenic potential, but we have already published or prepared papers indicating that some of the cells have a cardiomyogenic potential (Exp Cell Res. 313:2550, 2007; Stem Cells, 25:2017, 2007; J Gene Med, 6:833, 2004; Stem Cells, DOI: 10.1634/stemcells.2007-0826). Such a bioinformatics approach, i.e. hierarchical clustering analysis, is useful for nomination of “candidates”, and final proof for identifying morphogens/factors must be done via a cell biology approach using cell lines and a developmental methodology.