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Research Article

Neural Stem/Progenitor Cells from the Adult Human Spinal Cord Are Multipotent and Self-Renewing and Differentiate after Transplantation

  • Andrea J. Mothe mail,

    amothe@uhnres.utoronto.ca

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Tasneem Zahir,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Carlo Santaguida,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Douglas Cook,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Charles H. Tator

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Published: November 02, 2011
  • DOI: 10.1371/journal.pone.0027079

Reader Comments (2)

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2-yr-old donor

Posted by waisi on 30 Nov 2011 at 15:50 GMT

Hello. Nice and informative study!

Just wondering why you included spinal cord tissue from a 2-yr-old donor in your adult spinal cord NSPC study?

Thanks.

No competing interests declared.

RE: 2-yr-old donor

amothe replied to waisi on 01 Dec 2011 at 15:35 GMT

Thank you!
We had considered this and in the end decided to include the data. The phenotypic profile is different so we show this as a separate graph from the adult donors.
Thank you for your interest.

No competing interests declared.