Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

Liansheng Liu; Qian Li; Robert Sapolsky; Min Liao; Kshama Mehta; Aditi Bhargava; Pankaj J. Pasricha

doi:10.1371/journal.pone.0019498

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Peer-reviewed

Research Article

Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

Liansheng Liu,

Affiliation Division of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, California, United States of America
⨯
Qian Li,

Affiliation Department of Pharmacology and Toxicology, University of Kansas, Kansas City, Kansas, United States of America
⨯
Robert Sapolsky,

Affiliation Department of Biology, School of Humanities and Sciences, Stanford University, Stanford, California, United States of America
⨯
Min Liao,

Affiliation Department of Surgery, University of California San Francisco, San Francisco, United States of America
⨯
Kshama Mehta,

Affiliation Division of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, California, United States of America
⨯
Aditi Bhargava,

Affiliation Department of Surgery, University of California San Francisco, San Francisco, United States of America
⨯
Pankaj J. Pasricha

* E-mail: Pasricha@stanford.edu

Affiliation Division of Gastroenterology and Hepatology, Stanford University Medical Center, Stanford, California, United States of America
⨯

Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

Liansheng Liu,
Qian Li,
Robert Sapolsky,
Min Liao,
Kshama Mehta,
Aditi Bhargava,
Pankaj J. Pasricha

Published: May 12, 2011
https://doi.org/10.1371/journal.pone.0019498

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:49 GMT

The following articles represent some of the media coverage that has occurred for this paper:

Publication: New Scientist
Title: “Do early gut problems set the brain up for depression? - health - 20 May 2011 - New Scientist”
http://www.newscientist.c...

Publication: Opposing Views
Title: “Could Digestive Problems Cause Anxiety?”
http://www.opposingviews....

Publication: LA Times
Title: “Rodent of the Week: Stomach problems early in life linked to depression - latimes.com”
http://www.latimes.com/he...

Publication: Stanford Daily
Title: “Gastrointestinal research provides food for thought | Stanford Daily”
http://www.stanforddaily....

Publication: Scope - Stanford University School of Medicine
Title: “Scope - medical blog - Stanford University School of Medicine”
http://scopeblog.stanford...

Publication: Times of India
Title: “Digestive problems can give you depression - The Times of India”
http://timesofindia.india...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

Transient Gastric Irritation in the Neonatal Rats Leads to Changes in Hypothalamic CRF Expression, Depression- and Anxiety-Like Behavior as Adults

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:49 GMT