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closeCD prevalence
Posted by cevenol on 28 Apr 2008 at 17:29 GMT
Dr cicliterra is right, it seems the prevalence of CD is largely underestimate by authors. a finnish study (nov 2007) reports a doubling time of the "epidemy" of 10 years. their data (arrested in 2001) report a 2% prevalence. so this might give between 3-4 % in 2008...that quite important! so what's is going wrong? the wheat, the peoples , both...as these authors state..the genetic make up of the human being has not change since thousand of years...any comments wellcome. what impress me in this work is that we end up transmitting the CD to chimps! am I right?
RE: CD prevalence
ksestak replied to cevenol on 05 May 2008 at 18:49 GMT
We referred mostly to CD associated with clinical symptoms of disease. We agree with suggestion that subclinical forms of CD are largely underdiagnosed and not well studied. One of the objectives of our ongoing study with primates is to elucidate the factors that trigger transition of subclinical CD to clinical CD. Our primate model uses macaques not chimps. Diet of these primates (same like human diet) contains also gluten components which trigger the CD.
K. Sestak