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Research Article

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

  • Ankit Gupta equal contributor,

    equal contributor Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Pruthvi Nagilla equal contributor,

    equal contributor Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Hai-Son Le,

    Affiliation: Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

    X
  • Coulton Bunney,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Courtney Zych,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Anbupalam Thalamuthu,

    Affiliation: Human Genetics, Genome Institute of Singapore, Singapore

    X
  • Ziv Bar-Joseph,

    Affiliation: Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

    X
  • Sinnakaruppan Mathavan,

    Affiliation: Human Genetics, Genome Institute of Singapore, Singapore

    X
  • Velpandi Ayyavoo mail

    velpandi@pitt.edu

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: July 28, 2011
  • DOI: 10.1371/journal.pone.0022730

Reader Comments (20)

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Error

Posted by kwitwer1 on 05 Oct 2011 at 15:47 GMT

21 miRNAs and 444 mRNA more than 2-fold, with a statistical significance of p<0.05.
http://plosone.org/article/info:doi/10.1371/journal.pone.0022730#article1.front1.article-meta1.abstract1.p1

As per Table 3, only 16 miRNAs were differentially regulated with statistical significance of p<0.05. An additional five with p of 0.05 or greater are also listed in the Table.

No competing interests declared.