Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

Christopher J. Johnson; James P. Bennett; Steven M. Biro; Juan Camilo Duque-Velasquez; Cynthia M. Rodriguez; Richard A. Bessen; Tonie E. Rocke

doi:10.1371/journal.pone.0019836

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Peer-reviewed

Research Article

Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

Christopher J. Johnson ,

* E-mail: cjjohnson@usgs.gov

Affiliations Prion Research Laboratory, United States Geological Survey National Wildlife Health Center, Madison, Wisconsin, United States of America, Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
James P. Bennett,

Affiliations Prion Research Laboratory, United States Geological Survey National Wildlife Health Center, Madison, Wisconsin, United States of America, Institute for Environmental Studies, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
Steven M. Biro,

Affiliations Prion Research Laboratory, United States Geological Survey National Wildlife Health Center, Madison, Wisconsin, United States of America, Department of Bacteriology, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
Juan Camilo Duque-Velasquez,

Current address: Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada

Affiliation Grupo de Investigación CENTAURO, Facultad de Ciencias Agrarias, Universidad de Antioquia, Medellín, Antioquia, Colombia
⨯
Cynthia M. Rodriguez,

Affiliations Prion Research Laboratory, United States Geological Survey National Wildlife Health Center, Madison, Wisconsin, United States of America, Department of Bacteriology, University of Wisconsin, Madison, Wisconsin, United States of America
⨯
Richard A. Bessen,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Tonie E. Rocke

Affiliation Prion Research Laboratory, United States Geological Survey National Wildlife Health Center, Madison, Wisconsin, United States of America
⨯

Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

Christopher J. Johnson,
James P. Bennett,
Steven M. Biro,
Juan Camilo Duque-Velasquez,
Cynthia M. Rodriguez,
Richard A. Bessen,
Tonie E. Rocke

Published: May 11, 2011
https://doi.org/10.1371/journal.pone.0019836

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 22 Aug 2011 at 12:03 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Scientific American Blogs
Title: “Lichens vs. the Almighty Prion”
http://blogs.scientificam...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 25 Aug 2011 at 13:56 GMT

Further media coverage of this paper can be found below:

Publication: Scientific American
Title: “Observations: Natural Born Prion Killers: Lichens Degrade "Mad Cow" Related Brain Pathogen”
http://www.scientificamer...

Competing interests declared: PLoS ONE Staff

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Lichenology
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Proteases
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Immunoblotting
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Protein extraction
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Animal prion diseases
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Hamsters
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Protease inhibitors
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Serine proteases
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Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 22 Aug 2011 at 12:03 GMT

RE: Media Coverage of This Article

PLOS_ONE_Group replied to PLOS_ONE_Group on 25 Aug 2011 at 13:56 GMT