Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

Yuan-Ping Pang

doi:10.1371/journal.pone.0000058

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Peer-reviewed

Research Article

Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

Yuan-Ping Pang

*To whom correspondence should be addressed. E-mail: pang@mayo.edu

Affiliation Computer-Aided Molecular Design Laboratory, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
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Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

Yuan-Ping Pang

Published: December 20, 2006
https://doi.org/10.1371/journal.pone.0000058

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Correction made by the author

Posted by pang on 22 Dec 2006 at 23:52 GMT

Current anticholinesterase pesticides were developed during World War II and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (AChEs) in insects and in mammals.
http://plosone.org/article/info:doi/10.1371/journal.pone.0000058#article1.front1.article-meta1.abstract1.p1

Current anticholinesterase pesticides stem from World War II research on nerve gas and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (AChEs) in insects and in mammals.

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Pesticides
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Anopheles gambiae
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Serine proteases
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Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

Novel Acetylcholinesterase Target Site for Malaria Mosquito Control

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Correction made by the author

Posted by pang on 22 Dec 2006 at 23:52 GMT