Advertisement
Research Article

Does Pilocarpine-Induced Epilepsy in Adult Rats Require Status epilepticus?

  • Graciela Navarro Mora,

    Affiliation: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy

    X
  • Placido Bramanti,

    Affiliation: IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy

    X
  • Francesco Osculati,

    Affiliations: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy, IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy

    X
  • Asmaa Chakir,

    Affiliation: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy

    X
  • Elena Nicolato,

    Affiliation: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy

    X
  • Pasquina Marzola,

    Affiliation: Experimental MRI Center, Faculty of Medicine, University of Verona, Verona, Italy

    X
  • Andrea Sbarbati,

    Affiliation: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy

    X
  • Paolo Francesco Fabene mail

    paolo.fabene@univr.it

    Affiliation: Department of Morphological and Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona, Italy

    X
  • Published: June 02, 2009
  • DOI: 10.1371/journal.pone.0005759

Reader Comments (1)

Post a new comment on this article

Interesting paper but...

Posted by Damir on 05 Jul 2009 at 18:55 GMT

There are a few remediable weaknesses in this paper. The text needs re-editing, and the figures some serious redo. For example, the Y axes are often unlabeled, and the legends do nit fully explain what is being shown. Finally, the main interest of the paper lays in the absence of frank seizures after pilocarpine, but the EEG traces are not shown. Without this information it is difficult to evaluate the impact of this finding. It would be great to see these important finding appended to the paper.

No competing interests declared.