Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

Twila A. Mason; Elena Kolobova; Jiang Liu; Joseph T. Roland; Chin Chiang; James R. Goldenring

doi:10.1371/journal.pone.0027699

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Peer-reviewed

Research Article

Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

Twila A. Mason,

Affiliations Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Elena Kolobova,

Affiliations Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Jiang Liu,

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Joseph T. Roland,

Affiliations Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Chin Chiang,

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
James R. Goldenring

* E-mail: jim.goldenring@vanderbilt.edu

Affiliations Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯

Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

Twila A. Mason,
Elena Kolobova,
Jiang Liu,
Joseph T. Roland,
Chin Chiang,
James R. Goldenring

Published: November 15, 2011
https://doi.org/10.1371/journal.pone.0027699

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Posted by PLOS_ONE_Group on 30 Nov 2011 at 10:26 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: Business Wire
Title: “Preclinical Darinaparsin Study in PLoS ONE Publication”
http://www.businesswire.c...

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Competing interests declared: PLoS ONE Staff

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Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

Darinaparsin Is a Multivalent Chemotherapeutic Which Induces Incomplete Stress Response with Disruption of Microtubules and Shh Signaling

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Media Coverage of this Article

Posted by PLOS_ONE_Group on 30 Nov 2011 at 10:26 GMT