Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Peng Qi; Shu-qun Cheng; Hao Wang; Nan Li; Yue-feng Chen; Chun-fang Gao

doi:10.1371/journal.pone.0028486

Loading metrics

Open Access

Peer-reviewed

Research Article

Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Peng Qi ,

Contributed equally to this work with: Peng Qi, Shu-qun Cheng

Affiliation Department of Laboratory Medicine, Second Military Medical University, Eastern Hepatobiliary Hospital, Shanghai, China
⨯
Shu-qun Cheng ,

Contributed equally to this work with: Peng Qi, Shu-qun Cheng

Affiliation Department of Oncology Comprehensive Treatment, Second Military Medical University, Eastern Hepatobiliary Hospital, Shanghai, China
⨯
Hao Wang,

Affiliation Department of Laboratory Medicine, Second Military Medical University, Changzheng Hospital, Shanghai, China
⨯
Nan Li,

Affiliation Department of Oncology Comprehensive Treatment, Second Military Medical University, Eastern Hepatobiliary Hospital, Shanghai, China
⨯
Yue-feng Chen,

Affiliation Department of Laboratory Medicine, Second Military Medical University, Eastern Hepatobiliary Hospital, Shanghai, China
⨯
Chun-fang Gao

* E-mail: gaocf1115@163.com

Affiliation Department of Laboratory Medicine, Second Military Medical University, Eastern Hepatobiliary Hospital, Shanghai, China
⨯

Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Peng Qi,
Shu-qun Cheng,
Hao Wang,
Nan Li,
Yue-feng Chen,
Chun-fang Gao

Published: December 8, 2011
https://doi.org/10.1371/journal.pone.0028486

Reader Comments

Post a new comment on this article

Previous publication

Posted by kwitwer1 on 16 Mar 2012 at 21:29 GMT

o date, there have been no systematical reports on the role of circulating miRNAs in HCC
http://plosone.org/article/info:doi/10.1371/journal.pone.0028486#article1.body1.sec1.p3

It should be noted that HBV- and HBV/HCC-associated serum miRNAs were investigated by Li, et al. and published in 2010: Li LM, et al. "Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma." Cancer Research, Dec 1, 2010, 70(23). The investigators reported that 13 miRNAs were upregulated during HBV infection and could distinguish HBV from controls as well as HBV from HBV+ HCC.

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Hepatocellular carcinoma
Is the Subject Area "Hepatocellular carcinoma" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Cancer detection and diagnosis
Is the Subject Area "Cancer detection and diagnosis" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.

Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Previous publication

Posted by kwitwer1 on 16 Mar 2012 at 21:29 GMT