Protandim, a Fundamentally New Antioxidant Approach in Chemoprevention Using Mouse Two-Stage Skin Carcinogenesis as a Model

Open Access

Peer-reviewed

Research Article

Jianfeng Liu,

Affiliation Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
⨯
Xin Gu,

Affiliation Department of Pathology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
⨯
Delira Robbins,

Affiliation Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
⨯
Guohong Li,

Affiliation Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
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Runhua Shi,

Affiliation Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
⨯
Joe M. McCord,

Affiliation Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America
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Yunfeng Zhao

* E-mail: yzhao1@lsuhsc.edu

Affiliation Department of Pharmacology, Toxicology & Neuroscience, Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America
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Reader Comments

Importantly, at the end of the carcinogenesis study, both skin tumor incidence and multiplicity were reduced in the mice on the Protandim diet by 33% and 57% respectively, compared with those on basal diet.
http://plosone.org/article/info:doi/10.1371/journal.pone.0005284#article1.front1.article-meta1.abstract1.p1

Benefit of Protandim regarding skin cancer

No competing interests declared.

Diet
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Carcinogenesis
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Skin tissue
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Antioxidants
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Superoxide dismutase
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Skin tumors
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Inflammation
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