Dinosaur Peptides Suggest Mechanisms of Protein Survival

James D. San Antonio; Mary H. Schweitzer; Shane T. Jensen; Raghu Kalluri; Michael Buckley; Joseph P. R. O. Orgel

doi:10.1371/journal.pone.0020381

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Research Article

Dinosaur Peptides Suggest Mechanisms of Protein Survival

James D. San Antonio ,

* E-mail: jsanantonio@orthovita.com (JDSA); orgel@iit.edu (JPROO)

Affiliation Operations, Orthovita, Inc., Malvern, Pennsylvania, United States of America
⨯
Mary H. Schweitzer,

Affiliations Department of Marine, Earth and Atmospheric Sciences, North Carolina State University, Raleigh, North Carolina, United States of America, North Carolina Museum of Natural Sciences, Raleigh, North Carolina, United States of America, Museum of the Rockies, Montana State University, Bozeman, Montana, United States of America
⨯
Shane T. Jensen,

Affiliation Department of Statistics, The Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Raghu Kalluri,

Affiliations Division of Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts, United States of America
⨯
Michael Buckley,

Affiliations Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom, Department of Archaeology, The University of York, York, United Kingdom
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Joseph P. R. O. Orgel

* E-mail: jsanantonio@orthovita.com (JDSA); orgel@iit.edu (JPROO)

Affiliation Department of Biology, Pritzker Institute of Biomedical Science and Engineering, Illinois Institute of Technology, Chicago, Illinois, United States of America
⨯

Dinosaur Peptides Suggest Mechanisms of Protein Survival

James D. San Antonio,
Mary H. Schweitzer,
Shane T. Jensen,
Raghu Kalluri,
Michael Buckley,
Joseph P. R. O. Orgel

Published: June 8, 2011
https://doi.org/10.1371/journal.pone.0020381

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Results completely invalid

Posted by salzberg on 09 Jun 2011 at 10:34 GMT

Unfortunately for the authors, the peptides they examined are not from dinosaurs. They are contaminants from modern species. There have been several papers, including responses published right after her initial paper in Science, showing how and why Schweitzer's claims are unfounded.

No competing interests declared.

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Dinosaur Peptides Suggest Mechanisms of Protein Survival

Dinosaur Peptides Suggest Mechanisms of Protein Survival

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Results completely invalid

Posted by salzberg on 09 Jun 2011 at 10:34 GMT