Reader Comments

Post a new comment on this article

Reversible uncaging.

Posted by edboyden on 30 Mar 2007 at 22:06 GMT

uncaging
http://plosone.org/article/info:doi/10.1371/journal.pone.0000299#article1.body1.sec3.p2

An interesting paper demonstrating reversible light-activation and light-inactivation of an acetylcholine agonist, using azobenzene isomerization:

Chabala LD, Gurney AM, Lester HA.
Photoactivation and dissociation of agonist molecules at the nicotinic acetylcholine receptor in voltage-clamped rat myoballs.
Biophys J. 1985 Aug;48(2):241-6.