Carnitine Deficiency in OCTN2^−/− Newborn Mice Leads to a Severe Gut and Immune Phenotype with Widespread Atrophy, Apoptosis and a Pro-Inflammatory Response

• Srinivas Sonne,

  Affiliations Department of Pediatrics, Medical College of Georgia, Georgia Health Science University, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia, United States of America

  ⨯
• Prem S. Shekhawat ,

  * E-mail: shekhawatp@ecu.edu

  Affiliations Department of Pediatrics, Medical College of Georgia, Georgia Health Science University, Augusta, Georgia, United States of America, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia, United States of America

  ⨯
• Dietrich Matern,

  Affiliation Departments of Laboratory Medicine & Pathology, Medical Genetics, and Pediatric & Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America

  ⨯
• Vadivel Ganapathy,

  Affiliation Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia, United States of America

  ⨯
• Leszek Ignatowicz

  Affiliation Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Georgia Health Sciences University, Augusta, Georgia, United States of America

  ⨯