Perhaps it's an oversight, but I missed the part where the source code that the tax payers payed for via NIH Intramural funds, is released back to the public so that others may learn from, and enrich it. Neither could I find a link to download the source code from the application website. If the authors have no plan to release the source code, then it seems fitting for them to at least provide a rationale for holding the source back.
Otherwise, one might conclude that they intend to:
1) "corner the market" as the sole purveyors of this technology
or
2) re-purpose it for their own private gain
Even without presuming to know the authors' intentions, the lack of source code disclosure seems to fly in the face of the mission of PLOS, PLOS Labs, and most specifically the PLOS editorial policies for publishing papers about software, as listed here: http://www.plosone.org/st...
