Sustained Exendin-4 Secretion through Gene Therapy Targeting Salivary Glands in Two Different Rodent Models of Obesity/Type 2 Diabetes

• Giovanni Di Pasquale ,

  Contributed equally to this work with: Giovanni Di Pasquale, Ilaria Dicembrini

  Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

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• Ilaria Dicembrini ,

  Contributed equally to this work with: Giovanni Di Pasquale, Ilaria Dicembrini

  Affiliation Section of Endocrinology, Department of Clinical Pathophysiology, University of Florence, Florence, Italy

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• Laura Raimondi,

  Affiliation Department of Pharmacology, University of Florence, Florence, Italy

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• Claudio Pagano,

  Affiliation Endocrine-metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy

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• Josephine M. Egan,

  Affiliation Diabetes Section, National Institute on Aging and Health, Baltimore, Maryland, United States of America

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• Andrea Cozzi,

  Affiliation Department of Pharmacology, University of Florence, Florence, Italy

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• Lorenzo Cinci,

  Affiliation Section of Histology, Department of Anatomy, University of Florence, Florence, Italy

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• Andrea Loreto,

  Affiliation Department of Pharmacology, University of Florence, Florence, Italy

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• Maria E. Manni,

  Affiliation Department of Pharmacology, University of Florence, Florence, Italy

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• Silvia Berretti,

  Affiliation Department of Pharmacology, University of Florence, Florence, Italy

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• Annamaria Morelli,

  Affiliation Sexual Medicine and Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy

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• Changyu Zheng,

  Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

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• Drew G. Michael,

  Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

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• Mario Maggi,

  Affiliation Sexual Medicine and Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy

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• Roberto Vettor,

  Affiliation Endocrine-metabolic Laboratory, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy

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• John A. Chiorini ,

  * E-mail: jchiorini@dir.nidcr.nih.gov (JAC); c.rotella@dfc.unifi.it (CMR)

  Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

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• Edoardo Mannucci ,

  ¶These authors also contributed equally to this work.

  Affiliation Diabetes Agency, Careggi Teaching Hospital, Florence, Italy

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•  [ ... ],
• Carlo M. Rotella

  * E-mail: jchiorini@dir.nidcr.nih.gov (JAC); c.rotella@dfc.unifi.it (CMR)

  ¶These authors also contributed equally to this work.

  Affiliation Section of Endocrinology, Department of Clinical Pathophysiology, University of Florence, Florence, Italy

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