Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men

Nicholas A. Burd; Daniel W. D. West; Aaron W. Staples; Philip J. Atherton; Jeff M. Baker; Daniel R. Moore; Andrew M. Holwerda; Gianni Parise; Michael J. Rennie; Steven K. Baker; Stuart M. Phillips

doi:10.1371/journal.pone.0012033

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Open Access

Peer-reviewed

Research Article

Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men

Nicholas A. Burd,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Daniel W. D. West,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Aaron W. Staples,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Philip J. Atherton,

Affiliation School of Graduate Entry Medicine and Health, City Hospital, University of Nottingham, Derby, United Kingdom
⨯
Jeff M. Baker,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Daniel R. Moore,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Andrew M. Holwerda,

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯
Gianni Parise,

Affiliations Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada, Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada
⨯
Michael J. Rennie,

Affiliation School of Graduate Entry Medicine and Health, City Hospital, University of Nottingham, Derby, United Kingdom
⨯
Steven K. Baker,

Affiliation Department of Neurology, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Stuart M. Phillips

* E-mail: phillis@mcmaster.ca

Affiliation Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
⨯

Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men

Nicholas A. Burd,
Daniel W. D. West,
Aaron W. Staples,
Philip J. Atherton,
Jeff M. Baker,
Daniel R. Moore,
Andrew M. Holwerda,
Gianni Parise,
Michael J. Rennie,
Steven K. Baker

Published: August 9, 2010
https://doi.org/10.1371/journal.pone.0012033

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Reduced MPS and mTor with resistance training of multiple sites

Posted by overfiftylifter on 05 May 2011 at 20:20 GMT

I was wondering if as an example if one trained the quadriceps with the leg extension exercise and after completing this movement the trainee performed a biceps curl exercise, would the activity induced by the first exercise have a impact, perhaps reducing full potential MPS/signaling function at the biceps. I have read that training a distal large muscle area like the lower limb which produces increased systemic hormone activity had little effect on the small muscles of the upper limb but wonder if activating MPS/signaling at one site reduces the MPS/signaling at another? Does stress at one site effect the MPS at another? I hope my question is understood.

No competing interests declared.

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Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men

Low-Load High Volume Resistance Exercise Stimulates Muscle Protein Synthesis More Than High-Load Low Volume Resistance Exercise in Young Men

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Reduced MPS and mTor with resistance training of multiple sites

Posted by overfiftylifter on 05 May 2011 at 20:20 GMT