Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis

Michael P. Walsh; Ashish Chintakuntlawar; Christopher M. Robinson; Ijad Madisch; Balázs Harrach; Nolan R. Hudson; David Schnurr; Albert Heim; James Chodosh; Donald Seto; Morris S. Jones

doi:10.1371/journal.pone.0005635

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Peer-reviewed

Research Article

Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis

Michael P. Walsh,

Affiliation Department of Bioinformatics and Computational Biology, George Mason University, Manassas, Virginia, United States of America
⨯
Ashish Chintakuntlawar,

Affiliation Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Christopher M. Robinson,

Affiliation Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ijad Madisch,

Affiliation Insitut für Virologie, Medizinische Hochschule, Hannover, Germany
⨯
Balázs Harrach,

Affiliation Veterinary Medical Research Institute, Hungarian Academy of Sciences, Budapest, Hungary
⨯
Nolan R. Hudson,

Affiliation Clinical Investigation Facility, David Grant USAF Medical Center, Travis AFB, California, United States of America
⨯
David Schnurr,

Affiliation Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California, United States of America
⨯
Albert Heim,

Affiliation Insitut für Virologie, Medizinische Hochschule, Hannover, Germany
⨯
James Chodosh,

Affiliation Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Donald Seto,

Affiliation Department of Bioinformatics and Computational Biology, George Mason University, Manassas, Virginia, United States of America
⨯
Morris S. Jones

* E-mail: drmorrisj@yahoo.com

Affiliation Clinical Investigation Facility, David Grant USAF Medical Center, Travis AFB, California, United States of America
⨯

Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis

Michael P. Walsh,
Ashish Chintakuntlawar,
Christopher M. Robinson,
Ijad Madisch,
Balázs Harrach,
Nolan R. Hudson,
David Schnurr,
Albert Heim,
James Chodosh,
Donald Seto

Published: June 3, 2009
https://doi.org/10.1371/journal.pone.0005635

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Redefining Adenoviridae

Posted by mejones107 on 09 Jan 2010 at 05:52 GMT

This paper was amazing in several ways. First, it was the most interesting nove virus paper in 2009, because it had biological experiments as part of the study. Second, the recombination analysis was easy to follow and easy to read. Third, naming adenoviruses is something that needs to change. With the advent of whole genome sequencing, it is about time someone came out and decided that serology is cumbersome and outdated as a means of naming adenoviruses.

No competing interests declared.

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Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis

Evidence of Molecular Evolution Driven by Recombination Events Influencing Tropism in a Novel Human Adenovirus that Causes Epidemic Keratoconjunctivitis

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Redefining Adenoviridae

Posted by mejones107 on 09 Jan 2010 at 05:52 GMT