Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Luis Bujanda; Cristina Sarasqueta; Angel Cosme; Elizabeth Hijona; José M. Enríquez-Navascués; Carlos Placer; Eloisa Villarreal; Marta Herreros-Villanueva; María D. Giraldez; Meritxell Gironella; Francesc Balaguer; Antoni Castells

doi:10.1371/journal.pone.0051810

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Peer-reviewed

Research Article

Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Luis Bujanda ,

* E-mail: medik@telefonica.net

Affiliation Department of Gastroenterology, Donostia Hospital-Biodonostia Institute, University of Basque Country (UPV/EHU), Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas (CIBERehd), San Sebastián, Spain
⨯
Cristina Sarasqueta,

Affiliation Department of Epidemiology, CIBERESP, Donostia Hospital, San Sebastián, Spain
⨯
Angel Cosme,

Affiliation Department of Gastroenterology, Donostia Hospital-Biodonostia Institute, University of Basque Country (UPV/EHU), Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas (CIBERehd), San Sebastián, Spain
⨯
Elizabeth Hijona,

Affiliation Department of Gastroenterology, Donostia Hospital-Biodonostia Institute, University of Basque Country (UPV/EHU), Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas (CIBERehd), San Sebastián, Spain
⨯
José M. Enríquez-Navascués,

Affiliation Department of Surgery, Donostia Hospital, San Sebastián, Spain
⨯
Carlos Placer,

Affiliation Department of Surgery, Donostia Hospital, San Sebastián, Spain
⨯
Eloisa Villarreal,

Affiliation Department of Surgery, Donostia Hospital, San Sebastián, Spain
⨯
Marta Herreros-Villanueva,

Affiliation Department of Gastroenterology, Donostia Hospital-Biodonostia Institute, University of Basque Country (UPV/EHU), Centro de Investigación Biomédica en Enfermedades Hepáticas y Digestivas (CIBERehd), San Sebastián, Spain
⨯
María D. Giraldez,

Affiliation Department of Gastroenterology, Clinic Hospital, CIBERehd, IDIBAPS, Barcelona, Spain
⨯
Meritxell Gironella,

Affiliation Department of Gastroenterology, Clinic Hospital, CIBERehd, IDIBAPS, Barcelona, Spain
⨯
Francesc Balaguer,

Affiliation Department of Gastroenterology, Clinic Hospital, CIBERehd, IDIBAPS, Barcelona, Spain
⨯
Antoni Castells

Affiliation Department of Gastroenterology, Clinic Hospital, CIBERehd, IDIBAPS, Barcelona, Spain
⨯

Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Luis Bujanda,
Cristina Sarasqueta,
Angel Cosme,
Elizabeth Hijona,
José M. Enríquez-Navascués,
Carlos Placer,
Eloisa Villarreal,
Marta Herreros-Villanueva,
María D. Giraldez,
Meritxell Gironella

Published: January 2, 2013
https://doi.org/10.1371/journal.pone.0051810

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Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Posted by 0408luis on 17 Aug 2013 at 07:38 GMT

I've seen a phrase untranslated in the discussion (spanish to english). End of the third paragraph of the discussion

"In our study the expression on blood showed significant sifferences with controls and between controls and patients with stage I-II of CRC."

No competing interests declared.

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Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

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Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer

Posted by 0408luis on 17 Aug 2013 at 07:38 GMT